THE NOVEL POSITIVE ALLOSTERIC MODULATOR OF THE GABAB RECEPTOR, KK-92A, SUPPRESSES ALCOHOL SELF-ADMINISTRATION AND CUE-INDUCED REINSTATEMENT OF ALCOHOL SEEKING IN RATS

Positive allosteric modulators (PAMs) of the GABAB receptor (GABAB PAMs) are of interest in the addiction field due to their ability to suppress several behaviors motivated by drugs of abuse.KK-92A is a novel GABAB PAM found to attenuate intravenous self-administration of nicotine and reinstatement of nicotine seeking in rats.This present study was

This research aims to analyze the legal implications of the increase in space debris generated through space commercialization activities.This research uses a normative legal method using a qualitative approach to determine the application of law in commercial activities carried Heart Token out in space.The results of this study, namely: (1) the in

Introduction: Women and children in Uganda and other low- and middle-income countries are exposed to disproportionately high levels of household air pollution from Funko biomass smoke generated by smoke-producing cookstoves, especially in rural areas.This population is therefore particularly vulnerable to the negative health effects caused by house

Abstract Transformation acoustics, as an unconventional theory, provides a powerful tool to design various kinds of acoustic devices with excellent functionalities.However, the required ideal parameters, which are prescribed by the method, are both complex and hard to implement-even using acoustic metamaterials.Furthermore, simplified parameter mat

Prior research on the relationship between the taste, aroma and drinking utensils of beverages tends to focus on topics such as alcohol, sparkling beverages, juice, coffee, and COLOR CARE hot chocolate.There is limited research focused on the interdependence between the perception of teacups and the tea taste.The literature has not yet found any re